Magnesium sulfate

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Magnesium sulfate is a compound containing magnesium, sulfur and oxygen, with the formula MgSO4. It is a possible abortive treatment for migraines.

Not to be confused with the preventative treatment magnesium, which is typically administered orally, not intravenously.

Documented Dosage

1g intravenously over 15 minutes.[1]

Possible Side Effects

  • A brief flushed feeling / facial flusing[1][2]
  • Hypotension[2]
  • Lightheadedness[2]
  • Diarrhea[2]

Studies

One small study involved the abortive treatment of a migraine by administering 1g of magnesium sulfate over 15 minutes. 100% of the patients showed improvement, in either pain, or other symptoms. 87% of patients ultimately experienced lessening of pain. However, 86.6% also reported mild side effects to the treatment. [3]

References

  1. 1.0 1.1 Mauskop A, Altura BT, Cracco RQ, Altura BM."Intravenous magnesium sulfate rapidly alleviates headaches of various types." Headache. 1996 Mar;36(3):154-60. https://www.ncbi.nlm.nih.gov/pubmed/8984087 February 23, 2017.
  2. 2.0 2.1 2.2 2.3 Schnakenberg, Ellen. "Migraine Treatment: IV Magnesium Sulfate." Migraine.com. May 15, 2013. https://migraine.com/blog/migraine-treatment-iv-magnesium-sulfate/ February 23, 2017
  3. "Efficacy of intravenous magnesium sulfate in the treatment of acute migraine attacks." Gülhane Military Medical Academy Neurology Department, Ankara, Turkey. 2001. http://www.ncbi.nlm.nih.gov/pubmed/11251702 February 23, 2017