Aspirin, Acetaminophen, and Caffeine
The combination of aspirin, acetaminophen, and caffeine is used in over-the-counter (OTC) painkillers, usually specifically directed at headaches and/or migraines. This medication is most commonly used as an abortive treatment for migraines.
* Acetaminophen 260mg, Aspirin 500mg, Caffeine 32.5mg (Goody's Extra Strength Headache Powders). For ages 12+, 1 powder every 6 hours (not more than 4 in a 24 hour period). Drink a full glass of water with each dose.  * Acetaminophen 500mg, Aspirin 500mg, Caffeine 130mg (Excedrin Migraine Coated Caplets; 2 caplets). For ages 12+, 2 caplets with a full glass of water (not more than 2 caplets in a 24 hour period). 
- GoodysPowder.com. http://www.goodyspowder.com/products/extra-strength#drug-facts
- "Package Labeling Information." Excedrin.com. https://www.excedrin.com/products/migraine.shtml